{"id":352902,"date":"2025-05-14T05:22:32","date_gmt":"2025-05-14T05:22:32","guid":{"rendered":"https:\/\/euneighbourseast.eu\/?p=352902"},"modified":"2025-05-14T06:28:17","modified_gmt":"2025-05-14T06:28:17","slug":"un-singur-tratament-mai-putin-stres-o-cale-mai-sanatoasa-spre-recuperarea-dupa-o-interventie-chirurgicala-de-colon","status":"publish","type":"post","link":"https:\/\/euneighbourseast.eu\/ro\/news\/stories\/un-singur-tratament-mai-putin-stres-o-cale-mai-sanatoasa-spre-recuperarea-dupa-o-interventie-chirurgicala-de-colon\/","title":{"rendered":"Un singur tratament, mai pu\u021bin stres: o cale mai s\u0103n\u0103toas\u0103 spre recuperarea dup\u0103 o interven\u021bie chirurgical\u0103 de colon"},"content":{"rendered":"\n<p>O singur\u0103 injec\u021bie este suficient\u0103: nu mai sunt necesare tratamente antibiotice care dureaz\u0103 o s\u0103pt\u0103m\u00e2n\u0103 \u00eenainte de opera\u021bia pentru cancer intestinal. \u0218i nici microbiomul colonic nu mai este afectat inutil \u2013 comunitatea vital\u0103 de microorganisme care protejeaz\u0103 pere\u021bii intestinului nostru \u0219i ne sus\u021bine s\u0103n\u0103tatea \u00eenc\u0103 de la na\u0219tere. Un nou protocol antibiotic, mai restrictiv, pentru chirurgia de colon este unul dintre principalele rezultate ale proiectului COLONSTRESS, al c\u0103rui obiectiv a fost \u2013 printre altele \u2013 s\u0103 ofere dovezi privind modul \u00een care antibioticele pot altera mediul intestinal, \u0219i nu \u00een mod benefic.<\/p>\n\n\n\n<p>Este bine cunoscut faptul c\u0103 utilizarea ira\u021bional\u0103 a antibioticelor poate afecta grav s\u0103n\u0103tatea. Aceast\u0103 problem\u0103 s-a agravat \u00een timpul pandemiei de COVID-19, c\u00e2nd utilizarea prelungit\u0103 \u0219i excesiv\u0103 a antibioticelor a devenit mai frecvent\u0103 \u2013 adesea f\u0103r\u0103 a fi justificat\u0103 medical. De\u0219i au fost administrate pentru a combate infec\u021biile poten\u021biale, aceste tratamente au avut \u0219i consecin\u021be nedorite: ele nu vizeaz\u0103 doar agen\u021bii patogeni d\u0103un\u0103tori, ci perturb\u0103 \u0219i microbiota benefic\u0103. Aceste bacterii \u201ebune\u201d sunt esen\u021biale pentru echilibrul imunitar, digestie \u0219i starea general\u0103 de bine. \u201e<em>Prin perturbarea acestui ecosistem delicat, risc\u0103m s\u0103 sl\u0103bim una dintre cele mai importante ap\u0103r\u0103ri naturale ale corpului<\/em> \u2013 explic\u0103 Marcel Ciobanu, managerul proiectului COLONSTRESS. <em>Din p\u0103cate, dup\u0103 pandemie, \u00eent\u00e2lnim tot mai des disbioza, un dezechilibru \u00een comunit\u0103\u021bile microbiene, \u00een care grupurile de bacterii benefice sunt afectate<\/em>\u201d.<\/p>\n\n\n\n<div style=\"padding:56.25% 0 0 0;position:relative;\"><iframe src=\"https:\/\/player.vimeo.com\/video\/1083867001?badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture; clipboard-write; encrypted-media\" style=\"position:absolute;top:0;left:0;width:100%;height:100%;\" title=\"COLONSTRESS with RO subtitles\"><\/iframe><\/div><script src=\"https:\/\/player.vimeo.com\/api\/player.js\"><\/script>\n\n\n\n<p>A\u0219adar, utilizarea antibioticelor trebuie s\u0103 fie ra\u021bional\u0103 \u0219i adecvat\u0103. Dar care este abordarea optim\u0103 \u00een cazul unei interven\u021bii chirurgicale pentru cancer de colon? Una dintre cele mai frecvente complica\u021bii este infec\u021bia postoperatorie. Pentru a o preveni, este necesar\u0103 profilaxia chirurgical\u0103 cu antibiotice \u2013 ceea ce \u00eenseamn\u0103 c\u0103 antibioticul trebuie s\u0103 fie prezent \u00een \u021besut exact \u00een momentul \u00een care rana este deschis\u0103, adic\u0103 atunci c\u00e2nd riscul de infec\u021bie este cel mai ridicat. \u201e<em>Anterior <\/em>\u2013 continu\u0103 Ciobanu \u2013 <em>foloseam antibiotice timp de cinci p\u00e2n\u0103 la \u0219apte zile \u00eenainte de opera\u021bie pentru a preveni infectarea pl\u0103gii<\/em>\u201d. Asta \u00eensemna o \u00eenc\u0103rc\u0103tur\u0103 mare de antibiotice pentru pacient, pe parcursul mai multor zile, cu un stres major asupra microbiomului. Dar dac\u0103 ar exista o alternativ\u0103 mai eficient\u0103 \u0219i mai pu\u021bin invaziv\u0103? De exemplu, administrarea unei singure doze de antibiotic la \u00eenceputul anesteziei. Prin proiectul \u2013 finan\u021bat prin programul ENI CBC Rom\u00e2nia\u2013Republica Moldova \u2013 echipe de cercetare din ambele \u021b\u0103ri au comparat dou\u0103 protocoale antibiotice diferite pe grupuri similare de pacien\u021bi, desf\u0103\u0219ur\u00e2nd teste paralele pentru a identifica cea mai eficient\u0103 abordare. Patru sute de pacien\u021bi au fost testa\u021bi, c\u00e2te 200 \u00een fiecare \u021bar\u0103, iar 70 dintre ei au fost testa\u021bi de dou\u0103 ori, \u00een Chi\u0219in\u0103u \u0219i Ia\u0219i, pentru a valida metoda \u00een ambele institu\u021bii partenere. \u201e<em>Cercetarea noastr\u0103<\/em> \u2013 spune Ciobanu \u2013 <em>a demonstrat c\u0103 administrarea unei singure doze la \u00eenceputul anesteziei este mai eficient\u0103 \u00een prevenirea complica\u021biilor postoperatorii, f\u0103r\u0103 a provoca modific\u0103ri ale microbiomului colonic uman<\/em>\u201d.<\/p>\n\n\n\n<p>Cercetarea a fost o component\u0103 esen\u021bial\u0103 a proiectului. De fapt, unul dintre obiectivele COLONSTRESS a fost instruirea cercet\u0103torilor din Republica Moldova \u00een secven\u021bierea ADN, \u00een special \u00een metagenomica bacterian\u0103. Dup\u0103 cum explic\u0103 cercet\u0103torul Valeriu \u021au\u021buianu: \u201e<em>Deoarece colegii no\u0219tri din Ia\u0219i (Rom\u00e2nia) aveau mult mai mult\u0103 experien\u021b\u0103 \u00een acest domeniu, ne-au ghidat la fiecare pas \u2013 de la izolarea probelor p\u00e2n\u0103 la interpretarea datelor. \u00cempreun\u0103 \u2013 <\/em>continu\u0103 el<em> \u2013 am ajustat protocolul, ceea ce ne-a permis s\u0103 instruim \u0219i mai mul\u021bi cercet\u0103tori, astfel \u00eenc\u00e2t s\u0103 poat\u0103 utiliza singuri metoda \u0219i s\u0103 ob\u021bin\u0103 rezultate suficient de fiabile pentru utilizare clinic\u0103<\/em>.\u201d Iar p\u00e2n\u0103 la finalul activit\u0103\u021bilor, cele dou\u0103 institute de oncologie partenere au reu\u0219it s\u0103 stabileasc\u0103 o platform\u0103 comun\u0103 de biologie molecular\u0103.<\/p>\n\n\n<div class=\"pgc-sgb-cb wp-block-pgcsimplygalleryblock-slider \" data-gallery-id=\"6af90788\"style=&quot;min-height:560px&quot;><div class=\"sgb-preloader\" id=\"pr_6af90788\">\n\t<div class=\"sgb-square\" style=\"background:#d4d4d4\"><\/div>\n\t<div class=\"sgb-square\" style=\"background:#d4d4d4\"><\/div>\n\t<div class=\"sgb-square\" style=\"background:#d4d4d4\"><\/div>\n\t<div class=\"sgb-square\" style=\"background:#d4d4d4\"><\/div><\/div><div class=\"simply-gallery-amp pgc_sgb_slider \" style=\"display: none;\"><div class=\"sgb-gallery\"><div class=\"sgb-item\"><a href=\"https:\/\/euneighbourseast.eu\/ro\/?attachment_id=352872\" target=\"_blank\"><img decoding=\"async\" alt=\"\" width=\"300\" height=\"181\" loading=\"lazy\" src=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-2-picsart-aiimageenhancer-300x181.jpg\" srcset=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-2-picsart-aiimageenhancer-300x181.jpg 300w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-2-picsart-aiimageenhancer-1024x618.jpg 1024w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-2-picsart-aiimageenhancer-scaled.jpg 2560w\" sizes=\"250px\"\/><\/a><div class=\"sgb-item-caption\"><em>Cercetare de laborator<\/em><\/div><\/div><div class=\"sgb-item\"><a href=\"https:\/\/euneighbourseast.eu\/ro\/?attachment_id=352864\" target=\"_blank\"><img decoding=\"async\" alt=\"\" width=\"300\" height=\"165\" loading=\"lazy\" src=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/valeriu-tutuianu-researcher-picsart-aiimageenhancer-300x165.jpg\" srcset=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/valeriu-tutuianu-researcher-picsart-aiimageenhancer-300x165.jpg 300w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/valeriu-tutuianu-researcher-picsart-aiimageenhancer-1024x562.jpg 1024w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/valeriu-tutuianu-researcher-picsart-aiimageenhancer-scaled.jpg 2560w\" sizes=\"250px\"\/><\/a><div class=\"sgb-item-caption\"><em>Valeriu Tutuianu, cercet\u0103torul<\/em><\/div><\/div><div class=\"sgb-item\"><a href=\"https:\/\/euneighbourseast.eu\/ro\/?attachment_id=352888\" target=\"_blank\"><img decoding=\"async\" alt=\"\" width=\"300\" height=\"186\" loading=\"lazy\" src=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-300x186.jpg\" srcset=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-300x186.jpg 300w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-1024x634.jpg 1024w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-scaled.jpg 2560w\" sizes=\"250px\"\/><\/a><div class=\"sgb-item-caption\"><em>Valeriu face cercetare \u00een laborator<\/em><\/div><\/div><div class=\"sgb-item\"><a href=\"https:\/\/euneighbourseast.eu\/ro\/?attachment_id=352880\" target=\"_blank\"><img decoding=\"async\" alt=\"\" width=\"300\" height=\"163\" loading=\"lazy\" src=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-300x163.jpg\" srcset=\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-300x163.jpg 300w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-1024x557.jpg 1024w,https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-scaled.jpg 2560w\" sizes=\"250px\"\/><\/a><div class=\"sgb-item-caption\"><em>Preg\u0103tire pentru opera\u021bie<\/em><\/div><\/div><\/div><\/div><script type=\"application\/json\" 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laborator\",\"mime\":\"image\/jpeg\",\"type\":\"image\",\"width\":2560,\"height\":1586,\"sizes\":{\"thumbnail\":{\"height\":150,\"width\":150,\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-150x150.jpg\",\"orientation\":\"landscape\"},\"medium\":{\"height\":186,\"width\":300,\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-300x186.jpg\",\"orientation\":\"landscape\"},\"large\":{\"height\":634,\"width\":1024,\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-1024x634.jpg\",\"orientation\":\"landscape\"},\"full\":{\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/lab-research-3-picsart-aiimageenhancer-scaled.jpg\",\"height\":1586,\"width\":2560,\"orientation\":\"landscape\"}},\"imageMeta\":{\"aperture\":\"0\",\"credit\":\"\",\"camera\":\"\",\"caption\":\"\",\"created_timestamp\":\"0\",\"copyright\":\"\",\"focal_length\":\"0\",\"iso\":\"0\",\"shutter_speed\":\"0\",\"title\":\"\",\"orientation\":\"0\",\"keywords\":[]},\"meta\":false,\"postlink\":\"https:\/\/euneighbourseast.eu\/ro\/?attachment_id=352888\"},{\"id\":352880,\"title\":\"Preparation to surgery-Picsart-AiImageEnhancer\",\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-scaled.jpg\",\"link\":\"https:\/\/euneighbourseast.eu\/ro\/?attachment_id=352880\",\"alt\":\"\",\"description\":\"\",\"caption\":\"Preg\u0103tire pentru opera\u021bie\",\"mime\":\"image\/jpeg\",\"type\":\"image\",\"width\":2560,\"height\":1393,\"sizes\":{\"thumbnail\":{\"height\":150,\"width\":150,\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-150x150.jpg\",\"orientation\":\"landscape\"},\"medium\":{\"height\":163,\"width\":300,\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-300x163.jpg\",\"orientation\":\"landscape\"},\"large\":{\"height\":557,\"width\":1024,\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-1024x557.jpg\",\"orientation\":\"landscape\"},\"full\":{\"url\":\"https:\/\/euneighbourseast.eu\/wp-content\/uploads\/2025\/05\/preparation-to-surgery-picsart-aiimageenhancer-scaled.jpg\",\"height\":1393,\"width\":2560,\"orientation\":\"landscape\"}},\"imageMeta\":{\"aperture\":\"0\",\"credit\":\"\",\"camera\":\"\",\"caption\":\"\",\"created_timestamp\":\"0\",\"copyright\":\"\",\"focal_length\":\"0\",\"iso\":\"0\",\"shutter_speed\":\"0\",\"title\":\"\",\"orientation\":\"0\",\"keywords\":[]},\"meta\":false,\"postlink\":\"https:\/\/euneighbourseast.eu\/ro\/?attachment_id=352880\"}],\"itemsMetaDataCollection\":[]}<\/script><script>(function(){if(window.PGC_SGB && window.PGC_SGB.searcher){window.PGC_SGB.searcher.initBlocks()}})()<\/script><\/div>\n\n\n<p>Finally, the COLONSTRESS project has clearly demonstrated that the proper use of antibiotic prophylaxis can significantly lower the risk of complications in colorectal surgery. By limiting unnecessary antibiotic use, the rate of post-operative issues \u2013 such as allergic reactions, gut imbalance, or the need for reinterventions \u2013 has been reduced.<strong>&nbsp;<\/strong>\u201c<em>Patients have experienced shorter hospital stays,\u201d<\/em>&nbsp;concludes Ruslan Baltaga, Director of the institute of Oncology in Chisinau, <em>\u201cand overall, the quality of care has improved substantially\u201d.<\/em><\/p>\n\n\n\n<p><strong>Autor: <a href=\"https:\/\/interregtesimnext.eu\/author\/daniela\/\">Daniela Cavini<\/a>, <a href=\"https:\/\/interregtesimnext.eu\/\" target=\"_blank\" rel=\"noreferrer noopener\">TESIM<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>O singur\u0103 injec\u021bie este suficient\u0103: nu mai sunt necesare tratamente antibiotice care dureaz\u0103 o s\u0103pt\u0103m\u00e2n\u0103 \u00eenainte de opera\u021bia pentru cancer intestinal. \u0218i nici microbiomul colonic nu mai este afectat inutil \u2013 comunitatea vital\u0103 de microorganisme care protejeaz\u0103 pere\u021bii intestinului nostru \u0219i ne sus\u021bine s\u0103n\u0103tatea \u00eenc\u0103 de la na\u0219tere. Un nou protocol antibiotic, mai restrictiv, pentru chirurgia de colon este unul dintre principalele rezultate ale proiectului COLONSTRESS, al c\u0103rui obiectiv a fost \u2013 printre altele \u2013 s\u0103 ofere dovezi privind modul \u00een care antibioticele pot altera mediul intestinal, \u0219i nu \u00een mod benefic. Este bine cunoscut faptul c\u0103 utilizarea ira\u021bional\u0103 a<\/p>\n","protected":false},"author":21,"featured_media":352851,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","pgc_sgb_lightbox_settings":"","footnotes":""},"categories":[430],"tags":[2107],"post_flags":[1866],"countries":[1078],"eunlocking_industries":[],"locations":[],"opportunity_categories":[],"publication_types":[],"topics":[821,823,803,812],"yea_countries":[],"yea_event_places":[],"activity_types":[],"class_list":["post-352902","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-stories","tag-eu4moldova-2","post_flag-not-featured-ro","country-moldova","topic-research-innovation","topic-skills","topic-cross-border-cooperation","topic-health"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Un singur tratament, mai pu\u021bin stres: o cale mai s\u0103n\u0103toas\u0103 spre recuperarea dup\u0103 o interven\u021bie chirurgical\u0103 de colon - EU NEIGHBOURS east<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/euneighbourseast.eu\/ro\/news\/stories\/un-singur-tratament-mai-putin-stres-o-cale-mai-sanatoasa-spre-recuperarea-dupa-o-interventie-chirurgicala-de-colon\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un singur tratament, mai pu\u021bin stres: o cale mai s\u0103n\u0103toas\u0103 spre recuperarea dup\u0103 o interven\u021bie chirurgical\u0103 de colon - EU NEIGHBOURS east\" \/>\n<meta property=\"og:description\" content=\"O singur\u0103 injec\u021bie este suficient\u0103: nu mai sunt necesare tratamente antibiotice care dureaz\u0103 o s\u0103pt\u0103m\u00e2n\u0103 \u00eenainte de opera\u021bia pentru cancer intestinal. \u0218i nici microbiomul colonic nu mai este afectat inutil \u2013 comunitatea vital\u0103 de microorganisme care protejeaz\u0103 pere\u021bii intestinului nostru \u0219i ne sus\u021bine s\u0103n\u0103tatea \u00eenc\u0103 de la na\u0219tere. Un nou protocol antibiotic, mai restrictiv, pentru chirurgia de colon este unul dintre principalele rezultate ale proiectului COLONSTRESS, al c\u0103rui obiectiv a fost \u2013 printre altele \u2013 s\u0103 ofere dovezi privind modul \u00een care antibioticele pot altera mediul intestinal, \u0219i nu \u00een mod benefic. 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